Safety

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FDA slaps hold on trials of Gilead's CD47 drug magrolimab

The FDA has placed a partial clinical fold on clinical trials of Gilead Sciences' magrolimab, the centre piece of its $4.9 billion

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PureTech challenges Roche's Esbriet in head-to-head IPF tria...

Roche's idiopathic pulmonary fibrosis (IPF) therapy Esbriet is already being squeezed by its main rival in the market, and could come under renewed pressure if another competitor from PureT

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Young lonely man in a wheelchair on a balcony looking at the nature in the spring

Pfizer pauses Duchenne gene therapy trial after patient deat...

Pfizer has called a halt to a clinical trial of its gene therapy for Duchenne muscular dystrophy as it investigates the unexpected death of a young male patient.

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CDC eyes safety of J&J COVID jab as EU backs booster

Johnson & Johnson's also-ran COVID-19 vaccine has been cleared in the EU as a booster shot, although its role in the US could be impacted by new data on rare blood clots.

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FDA delays review of Moderna COVD jab in adolescents

The FDA has said it needs more time to review Moderna's application for emergency use of its COVID-19 vaccine mRNA-1273 in children aged 12 to 17, as it looks at data on heart inflammation

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FDA halts Allogene CAR-T trial after safety scare

A phase 1 trial of Allogene's of-the-shelf CAR-T for lymphoma has been placed on hold by the FDA, after a "chromosomal abnormality" was seen in a patient receiving the cell therapy.