Safety

News

Young lonely man in a wheelchair on a balcony looking at the nature in the spring

Pfizer pauses Duchenne gene therapy trial after patient deat...

Pfizer has called a halt to a clinical trial of its gene therapy for Duchenne muscular dystrophy as it investigates the unexpected death of a young male patient.

News

CDC eyes safety of J&J COVID jab as EU backs booster

Johnson & Johnson's also-ran COVID-19 vaccine has been cleared in the EU as a booster shot, although its role in the US could be impacted by new data on rare blood clots.

News

FDA delays review of Moderna COVD jab in adolescents

The FDA has said it needs more time to review Moderna's application for emergency use of its COVID-19 vaccine mRNA-1273 in children aged 12 to 17, as it looks at data on heart inflammation

News

FDA halts Allogene CAR-T trial after safety scare

A phase 1 trial of Allogene's of-the-shelf CAR-T for lymphoma has been placed on hold by the FDA, after a "chromosomal abnormality" was seen in a patient receiving the cell therapy.

News

Takeda halts trial of orexin drug in narcolepsy on safety gr...

Japanese drugmaker Takeda has suspended dosing in phase 2 trials of its orexin agonist TAK-994, saying it had encountered a "safety signal" in the study.

News

Astellas reports fourth death in halted gene therapy trial

There has been a fourth patient fatality in Astellas' clinical trial of its AT132 gene therapy for the rare disease X-linked myotubular myopathy (XLMTM), which has been halted twice due to