2nd ADC Payload Summit
The 2nd ADC Payload Summit (May 6-8 | Boston, MA). This is the first and only conference exclusively focusing on ADC payloads, helping you to reimagine the medicinal chemistry of traditional cytotoxic payloads while scouting the next generation of ADC payload innovations.
With novel payload categories such as degraders, RNA polymerase II inhibitors, immunomodulators, gene silences, and splice modulators entering the clinic, don't miss this opportunity to meet with fellow peers to explore the benefits of these diverse mechanisms of action to develop the next blockbuster ADC.
Here are some of the agenda highlights you cannot afford to miss:
- Gain insights from Eisai on “Engineering STING/TLR Agonist Payloads to Amplify Anti-Tumor Immune Responses Without Triggering Cytokine Induction” discussing the synthesis and PK profile of E7766 STING agonist payload for PSMA targeting ADC, analyzing in vitro and in vivo studies showing mitigation of ISAC tox concerns affiliated with cytokine induction, and exploring the therapeutic niche and potential of STING agonist payloads.
- Join Takeda in “Navigating the Evolution of ADC Payloads – From Topo1 Success to Future Innovation” to discuss why Topo1 inhibitors dominated the clinic so fast, what other modes of action and payload classes need to do to match that clinical success, and where there is whitespace for novel payloads to gain ground in a competitive ADC landscape.
- Hear from Merck on “Accelerating Degrader-Antibody Conjugate Design Through Strategic Integration of Traditional ADC & Expertise in TPD” to learn about translating physicochemical property optimization strategies from traditional ADCs to address unique degrader payload solubility and stability challenges.
Take a look at the full speaker faculty and session details.
Across 3 days, you can gain critical insights to characterize the physicochemical and pharmacological properties of emerging payloads, enhance structure-activity relationships through innovative payload-linker designs, and benchmark payload selection strategies tailored to specific indications.
Join 80+ of your peers at the only meeting exclusively dedicated to showcasing novel payloads and addressing the challenges of payload optimization.
