On GDF-15 neutralisation and cachexia, with CatalYm

Oncology
CatalYm's Scott Clarke from ESMO 2026

As ESMO 2026 continues to get underway, pharmaphorum web editor Nicole Raleigh spoke with Scott Clarke, CEO of CatalYm, a company pioneering GDF-15 neutralisation to address cancer resistance and cachexia.

Clarke discusses updated results from the ongoing Phase 2 GDFATHER-NEO trial of visugromab, a first-in-class anti-GDF-15 antibody, in combination with nivolumab as neoadjuvant treatment for patients with muscle-invasive bladder cancer are scheduled for a rapid oral presentation this weekend.

Watch the conversation and keep on eye on our ESMO 2026 updates here.