TIGIT

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GSK pays $1.2bn for liver drug as it culls TIGIT programme

GSK decided to abandon a TIGIT-targeted drug for cancer this week, then hatched a plan to replace it with a candidate for liver disease MASH.

News

BeiGene abandons TIGIT antibody after lung cancer flop

BeiGene has decided to stop the development of its TIGIT-targeting drug ociperlimab in yet another setback for the drug class.

News

End of the line for MSD's TIGIT, LAG-3 cancer drugs

MSD has stopped development of anti-TIGIT antibody vibostolimab and anti-LAG-3 antibody favezelimab, blowing a hole in its immuno-oncology pipeline.

News

ESMO: GSK, iTeos bring some optimism back to TIGIT

GSK and iTeos anti-TIGIT antibody belrestotug showed efficacy in a phase 2 trial in PD-L1-positive non-small cell lung cancer (NSCLC), providing some much-needed positive news for the belea

News

Person with their hand covering their face

More bad news for TIGIT as MSD stops another trial

Another TIGIT trial failure has been abandoned, casting a shadow once again over the target as a cancer immunotherapy strategy.

News

BMS ducks out of $1.56bn TIGIT alliance with Agenus

Bristol-Myers Squibb has handed back rights to a TIGIT drug partnered with Agenus, ending an alliance that could have been worth up to $1.56 billion to the biotech.

GSK pays $1.2bn for liver drug as it culls TIGIT programme

BeiGene abandons TIGIT antibody after lung cancer flop

End of the line for MSD's TIGIT, LAG-3 cancer drugs

ESMO: GSK, iTeos bring some optimism back to TIGIT

More bad news for TIGIT as MSD stops another trial

BMS ducks out of $1.56bn TIGIT alliance with Agenus

Treating primary bone cancer: The potential of listeria-base...

The value of a partner, globally and locally

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