TIGIT

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ESMO: GSK, iTeos bring some optimism back to TIGIT

GSK and iTeos anti-TIGIT antibody belrestotug showed efficacy in a phase 2 trial in PD-L1-positive non-small cell lung cancer (NSCLC), providing some much-needed positive news for the belea

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More bad news for TIGIT as MSD stops another trial

Another TIGIT trial failure has been abandoned, casting a shadow once again over the target as a cancer immunotherapy strategy.

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BMS ducks out of $1.56bn TIGIT alliance with Agenus

Bristol-Myers Squibb has handed back rights to a TIGIT drug partnered with Agenus, ending an alliance that could have been worth up to $1.56 billion to the biotech.

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Roche’s TIGIT drug linked to worse outcomes in NSCLC trial

Roche’s anti-TIGIT drug tiragolumab has failed a lung cancer study, denting enthusiasm for the programme just as there were signs that it was getting back on track after a series of disappo

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MSD has another TIGIT programme setback

A phase 3 trial of MSD’s anti-TIGIT antibody vibostolimab and PD-1 inhibitor pembrolizumab has been abandoned after a high rate of discontinuations rendered the study futi

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Gilead, Arcus say TIGIT combo encouraging in GI cancer

Gilead and Arcus’ efforts to rebuild confidence in TIGIT as a drug target for cancer immunotherapies have shuffled forwards again, with new data showing signs of efficacy

ESMO: GSK, iTeos bring some optimism back to TIGIT

More bad news for TIGIT as MSD stops another trial

BMS ducks out of $1.56bn TIGIT alliance with Agenus

Roche’s TIGIT drug linked to worse outcomes in NSCLC trial

MSD has another TIGIT programme setback

Gilead, Arcus say TIGIT combo encouraging in GI cancer

Gene therapy firm Kate Tx snapped up by Novartis for $1.1bn

Coming soon: The Life Sciences Industry Report 2025 – insigh...

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