TIGIT

News

MSD has another TIGIT programme setback

A phase 3 trial of MSD’s anti-TIGIT antibody vibostolimab and PD-1 inhibitor pembrolizumab has been abandoned after a high rate of discontinuations rendered the study futi

News

Gilead, Arcus say TIGIT combo encouraging in GI cancer

Gilead and Arcus’ efforts to rebuild confidence in TIGIT as a drug target for cancer immunotherapies have shuffled forwards again, with new data showing signs of efficacy

News

'Inadvertent' leak teases survival benefit for Roche's TIGIT

In an unusual development, Roche has put out a statement this morning acknowledging an "inadvertent disclosure" of data from its SKYSCRAPER-01 study of anti-TIGIT drug tir

News

TIGIT underwhelms again as Novartis ducks out

The role of TIGIT as a target for immuno-oncology therapies has been called into question again after it was revealed that Novartis handed back rights to a drug partnered

News

ASCO: TIGIT returns with Roche, Gilead data

A year ago, enthusiasm for a new generation of cancer immunotherapies targeting TIGIT started to wane, after Roche’s tiragolumab was hit by two

News

Merck suffers a setback in its TIGIT programme

Missed endpoint in mid-stage study in lung cancer is a worry after other TIGIT failures.

MSD has another TIGIT programme setback

Gilead, Arcus say TIGIT combo encouraging in GI cancer

'Inadvertent' leak teases survival benefit for Roche's TIGIT

TIGIT underwhelms again as Novartis ducks out

ASCO: TIGIT returns with Roche, Gilead data

Merck suffers a setback in its TIGIT programme

GSK sets up Nucala and Dupixent showdown in COPD

Health Trends 2025: Reimagining What's Possible

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TIGIT

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