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ADC Therapeutics slumps on cancer drug safety scare

Shares in ADC Therapeutics fell more than 50% after a non-Hodgkin lymphoma trial showed more deaths with its Zynlonta drug compared to a control.

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NICE backs Roche's non-Hodgkin lymphoma drug Columvi

NICE backs NHS use of Roche's Columvi as a second-line therapy for a form of non-Hodgkin lymphoma affecting thousands of people in the UK each year.

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Approval moves Columvi earlier in DLBCL treatment pathway

Roche has claimed a first-in-class approval in the EU for Columvi in relapsed/refractory diffuse large B-cell lymphoma (DLBCL).

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MSD starts pivotal trial of ROR1 drug in first-line lymphoma

MSD has started a phase 3 trial of ROR1-directed ADC zilo-V as a treatment for previously untreated diffuse large B-cell lymphoma.

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ASH: MSD’s ROR1 drug hits the target in first-line lymphoma

The results of a phase 2 trial of MSD’s anti-ROR1 ADC zilovertamab vedotin back up the company's decision to start a phase 3 trial in DLBCL.

News

After FDA no, Regeneron gets yes from EU on odronextamab

Regeneron's CD20xCD3 bispecific antibody for non-Hodgin lymphoma (NHL) has been approved in Europe, five months after it was turned down by the FDA in the US.

ADC Therapeutics slumps on cancer drug safety scare

NICE backs Roche's non-Hodgkin lymphoma drug Columvi

Approval moves Columvi earlier in DLBCL treatment pathway

MSD starts pivotal trial of ROR1 drug in first-line lymphoma

ASH: MSD’s ROR1 drug hits the target in first-line lymphoma

After FDA no, Regeneron gets yes from EU on odronextamab

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