amyotrophic lateral sclerosis

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FDA clears trial of 'vectorised' ALS antibody from VectorY

VectorY has been cleared by the FDA to start human trials of a drug against a target implicated in up to 97% of amyotrophic lateral sclerosis cases.

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NRG raises £50m to start trials of Parkinson's, ALS drug

NRG Therapeutics' oversubscribed Series B will fund first-in-human trials of a drug targeting mitochondrial dysfunction in neurodegenerative diseases.

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Alchemab's chief executive, Jane Osbourn

Lilly forges a $415m ALS alliance with UK biotech Alchemab

Eli Lilly has added another candidate to a growing pipeline of therapies for ALS, tapping Alchemab for an antibody sourced from 'resilient' patients.

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Denali's ALS programme suffers another setback

Prospects for Denali Therapeutics' experimental medicine for amyotrophic lateral sclerosis have taken another tumble.

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Four more drugs in keenly watched ALS trial miss the mark

ALS candidates from Biohaven, Prilenia, Clene, and UCB were unable to slow disease progression in the study, but two showed signs of efficacy.

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Denali slides after ALS drug flunks clinical test

Another clinical trial setback disappoints the ALS patient community, this time involving Denali's eIF2B agonist DNL343.

FDA clears trial of 'vectorised' ALS antibody from VectorY

NRG raises £50m to start trials of Parkinson's, ALS drug

Lilly forges a $415m ALS alliance with UK biotech Alchemab

Denali's ALS programme suffers another setback

Four more drugs in keenly watched ALS trial miss the mark

Denali slides after ALS drug flunks clinical test

NHS "isn't delivering equitable care for rare diseases"

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amyotrophic lateral sclerosis

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