From R&D to ROI: AI’s impact on pharma commercialisation
Artificial intelligence (AI) has been a transformative force in the pharmaceutical industry for over a decade. AI can be categorised into two distinct types: “left-brain AI” and “right-brain AI.” The former, also known as classical AI, has been instrumental in predictive tasks such as finding patients, aiding in R&D to discover new assets and optimising supply chains.
There are currently over 100 AI-driven drug discoveries in the pipelines of pharmaceutical companies worldwide. AI is also being used to create connected personal experiences for patients and providers, streamline regulatory reviews, personalise content, and develop hyper-informed treatment pricing models.
While classical AI has already revolutionised the R&D side of pharma, the focus is now shifting to the commercial side, where generative AI, or “right-brain AI,” comes into play. This type of AI is more intuitive and creative, capable of reasoning and understanding complex scenarios.
But, pharma is experiencing some of the scaling challenges that other enterprises face, as over 80% of companies are experimenting, but only 11% are achieving notable ROI, highlighting the nascent phase of this technology.
Understanding the disconnect
The discrepancy in ROI is not unusual in the early stages of a technological wave. Drawing parallels to past innovations, consider the first autonomous car race in the Mojave Desert in 2004, sponsored by DARPA.
Twenty years later, we still aren’t anywhere near scaling autonomous cars on the road. Similarly, the evolution of e-commerce, with companies such as Amazon, which was founded in 1994, has seen only 25% to 30% of retail sales move online after 30 years. This doesn’t mean these technologies aren’t massively impactful.
As futurist Roy Amara observed, “We tend to overestimate the effect of a technology in the short run and underestimate the effect in the long run.” While the pharmaceutical industry is in the early innings of the AI wave, the long-term potential remains vast and transformative.
The iPhone moment for pharma
Reflecting on the mobile wave, the current AI revolution can be likened to the “iPhone moment.” Just as the iPhone democratised innovation for digital health, AI has the potential to transform patient and healthcare provider (HCP) engagement in pharma.
We now have over 350,000 digital health apps available with over 250 being released each day. We expect to see the same kind of surge in AI-enabled health solutions in the future, but like digital health apps, not all of them will drive value for patients.
Challenges of AI implementation
And while AI has so many opportunities, they do not come without challenges.
One of the significant challenges of AI implementation is that 50% of AI pilots are not going into production. This is due to various reasons, including data quality, regulatory compliance, and cultural resistance. To address these challenges, it’s crucial that the pharma industry, as it adopts AI, bring HCPs along for the ride.
Successful digital health apps, such as China’s Good Doctor from Ping An, include a clinician side, such as Ask Bob, which has 430,000 clinicians using its AI-driven clinical assistant. Developing tools without involving those affected by them can lead to failure, as seen in the early days of digital health.
Leveraging partnerships and ecosystems: A fine balance
In the AI-first world, determining the overall strategy should not be outsourced too often to partners.
Pharmaceutical companies know their use cases best and should leverage an ecosystem of tech partners to build, buy or borrow solutions.
This approach will ensure the technology aligns with the company’s strategic goals and addresses specific business problems.
The three R’s of AI implementation
When it comes to implementing AI in the pharmaceutical industry, it’s crucial to recognise that from what we have observed in recent years, only 10% of the effort is about the technology itself. Another 20% is about the model, but a significant 70% revolves around people, behaviour change, culture, and mindset. This understanding is essential for addressing the challenges and maximising the benefits of AI.
Responsibility involves establishing a solid foundation of governance and accountability. Every employee must understand the boundaries and goals of AI use within the organisation.
This means having a clear framework that outlines how the company will implement AI and what the boundaries are. This backbone of governance ensures that everyone is on the same page and that ethical considerations are at the forefront of AI implementation.
Reliability focuses on selecting use cases that not only are relevant, but also can clearly demonstrate the “why” behind them. It’s important to recognise that generative AI comes with a certain level of unpredictability. Hallucination, or the generation of incorrect or nonsensical information, is a feature, not a bug, of generative AI.
While we can curate data and build guardrails, there will always be some level of error. The key is to determine whether the organisation can tolerate this unpredictability in the chosen use case. Ensuring reliability means being prepared to manage and mitigate these risks effectively.
ROI should be considered early in the process, building at least a skeleton business case around all three factors: responsibility, reliability and ROI. This involves answering the “why,” giving people permission to explore and innovate, and providing them with the necessary governance framework. By doing so, the organisation can move forward, creating a culture that embraces AI while ensuring that it delivers real value.
The future of AI in pharma is promising, with the potential to free up human capacity for more value-added work such as creativity and strategy. Upskilling on both AI and soft skills, such as agility and critical thinking, will be crucial.
So, what’s the end goal? In my mind, it’s harnessing AI responsibly to drive real-world impact and improve patient outcomes. However, to do so requires careful implementation, collaboration and a focus on creating real value. By addressing the challenges and leveraging the opportunities, the pharmaceutical industry can transform its commercial model with AI, creating a better healthcare experience for everyone.
About the author
Scott Snyder serves as EVERSANA’s chief digital officer, driving digital transformation for employees, clients, and the patients we serve. He brings more than 30 years of experience in emerging technologies and digital transformation across both global 1000 companies and startup ventures. Snyder is the co-author of Goliath’s Revenge, a book focused on how established companies can turn the table through digital disruption. He earned his B.S., M.S., and Ph.D. in Systems Engineering from the University of Pennsylvania.
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